Trans R Soc Trop Med Hyg. 2013 Aug;107(8):502-10.

Intestinal parasites in HIV-seropositive patients in the Continental Region of Equatorial Guinea: its relation with socio-demographic, health and immune systems factors.

Roka M, Goñi P, Rubio E, Clavel A.

Area of Parasitology, Department of Microbiology, Preventive Medicine and Public Health, Faculty of Medicine, University of Zaragoza, C/Domingo Miral s/n, 50009 Zaragoza, Spain.

 

ABSTRACT

BACKGROUND: Prevalence of intestinal parasitic infections in HIV-positive people and its association with clinical and socioeconomic factors has been investigated on the mainland of Equatorial Guinea, in order to define the precise measures for improvement of their quality of life.

METHODS: In August 2010, 273 HIV-positive and 60 HIV-negative were recruited. A sample of faeces, T-CD4+ cell counts, and clinical, socioeconomic and demographic data were collected from each patient. Stool samples were analysed by microscopy and immunochromatography. Data were analysed by Pearson’s χ2 test and the risk of each factor was measured by odds ratio bivariate analysis.

RESULTS: Two hundred and ten (76.9%) HIV-positive participants were infected by intestinal parasites and 16 parasite species were identified; 246 (48.9%) were pathogenic helminths, 159 (22.9%) pathogenic protozoa and 142 (28.2%) opportunistic protozoa. Trichuris trichiura, Entamoeba histolytica/dispar/moshkovskii, Ascaris lumbricoides and Giardia duodenalis were the most prevalent parasites; 52 (86.7%) of HIV-negative participants were parasitized. HIV was related to co-infection by Entamoeba spp., E. nana and Blastocystis hominis.

CONCLUSIONS: The high rates of parasitic infections found highlights the urgent need of environmental sanitation, health education and water distribution actions, as well as early diagnosis and treatment of intestinal parasites.

KEYWORDS: Equatorial Guinea, Evironmental sanitation, HIV, Intestinal parasites, Socioeconomic factors

PMID: 23783759

 

ACKNOWLEDGEMENTS

We thank the Ministry of Health and Social Welfare of Equatorial Guinea to validate our research and grant permission for its realization. We also thank the WHO (Equatorial Guineans office) for their support to the project, and people living with HIV and their families who freely agreed to participate in this project. Present research was supported in partly by the FIS Project PI09/01585 and BG limited Equatorial Guinea. Operon SL (Zaragoza, Spain) donated the rapid immunochromatography materials employed in the study and the Clinical Analysis Laboratory of Castroverde (Malabo, Equatorial Guinea) has contributed with some of the materials used in Bata, the Microbiology Laboratory of Regional Hospital Bata and the Health Center Maria Rafols which allowed us to use their facilities to carry out the work in this city. M. Roka is a recipient of a grant from the AECID.

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