Diabetes and Obesity

2016 Dec

 

2016 Apr-June

1. Ghrelin O-acyltransferase knockout mice show resistance to obesity when fed high-sucrose diet. J Endocrinol. 2016 228(2):115-125

3. Combining citrulline to atorvastatin preserves glucose homeostasis in a murine model of diet-induced obesity. Br J Pharmacol. 2015 Oct;172(20):4996-5008.

5. Diet/Energy Balance Affect Sleep and Wakefulness Independent of Body Weight. Sleep. 2015 Dec 1;38(12):1893-903

7. Incidence and care-related costs of severe hypoglycaemia requiring emergency treatment in Andalusia (Spain): the PAUEPAD project. Diabet Med. 2015 Nov;32(11):1520-6.

9. The VGF-derived peptide TLQP-62 modulates insulin secretion and glucose homeostasis. J Mol Endocrinol. 2015 Jun;54(3):227-39.

11. Visceral fat is better related to impaired glucose metabolism than body mass index after kidney transplantation. Transpl Int. 2015 Oct;28(10):1162-71.

14. Decreased insulin secretion and glucose clearance in exocrine pancreas-insufficient pigs. Exp Physiol. 2016 Jan 1;101(1):100-12.

16. A Comparison of the Effects of the GLP-1 Analogue Liraglutide and Insulin Glargine on Endothelial Function and Metabolic Parameters: A Randomized, Controlled Trial Sapporo Athero-Incretin Study 2 (SAIS2). PLoS One. 2015 Aug 18;10(8):e0135854.

18. Hypoglycemic and Antidiabetic Effect of Pleurotus sajor-caju Aqueous Extract in Normal and Streptozotocin-Induced Diabetic Rats. Biomed Res Int. 2015;2015:214918.

20. Rapid increase in fibroblast growth factor 21 in protein malnutrition and its impact on growth and lipid metabolism. British Journal of Nutrition 2015 Nov 14;114(9):1410-18.

22. Electrophysiological assessments of the motor pathway in diabetic patients with compressive cervical myelopathy. J Neurosurg Spine. 2015 Dec;23(6):707-14

24. Lecithin:Cholesterol Acyltransferase (LCAT) Deficiency Promotes Differentiation of Satellite Cells to Brown Adipocytes in a Cholesterol-dependent Manner. J Biol Chem. 2015 Dec 18;290(51):30514-29.

26. Aquaporin 11 variant associates with kidney disease in type 2 diabetic patients. Am J Physiol Renal Physiol. 2016 Mar 1;310(5):F416-25.

28. The Application of Systems Science to Addressing Obesity at the Workplace: Tapping into Unexplored Potential. J Occup Environ Med. 2016 Feb;58(2):123-6.

 

 

2. Using synchronous distance education to deliver a weight loss intervention:  a randomized trial. Obesity. 2016 Jan;24(1):44-50

4. Multicenter investigation of lifestyle-related diseases and visceral disorders in thalidomide embryopathy at around 50 years of age. Birth Defects Res A Clin Mol Teratol. 2015 Sep;103(9):787-93.

6. Obesity: An overview of possible role(s) of gut hormones, lipid sensing and gut microbiota. Metabolism. 2016 Jan;65(1):48-65.

8. Disturbance of the intestinal microbial community by ursolic acid contributes to its function as a regulator of fat deposition. J Funct Food.2015 Apr;14:456-468.

10. GLP-2 as Beneficial Factor in the Glucose Homeostasis in Mice Fed a High Fat Diet. J Cell Physiol. 2015 230(12):3029-3036.

12. Ganglioside GM1 Contributes to the State of Insulin Resistance in Senescent Human Arterial Endothelial Cells. J Biol Chem. 2015 Oct 16;290(42):25475-86.

15. Alginates in Pharmaceutics and Biomedicine: Is the Future so Bright? Curr Pharm Des. 2015;21(33):4917-35.

17. Chronic Co-Administration of Sepiapterin and l-Citrulline Ameliorates Diabetic Cardiomyopathy and Myocardial Ischemia/Reperfusion Injury in Obese Type 2 Diabetic Mice. Circ Heart Fail. 2016 Jan;9(1):e002424.

19. Results of Automated Retinal Image Analysis for Detection of Diabetic Retinopathy from the Nakuru Study, Kenya. PLoS One. 2015 Oct 1;10(10):e0139148.

21. The Diabetes Visual Function Supplement Study (DiVFuSS). Br J Ophthalmol. 2016 Feb;100(2):227-34.

23. Urinary Exosomal miRNA Signature in Type II Diabetic Nephropathy Patients. PLoS One. 2016 Mar 1;11(3):e0150154.

25. Paternal long-term exercise programs offspring for low energy expenditure and increased risk for obesity in mice. FASEB J. 2016 Feb;30(2):775-84.

27. Clopidogrel Protects Endothelium by Hindering TNFα-Induced VCAM-1 Expression through CaMKKβ/AMPK/Nrf2 Pathway. J Diabetes Res. 2016;2016:9128050.

29. Integrating palliative care with usual care of diabetic foot wound. Diabetes Metab Res Rev. 2016 Jan;32 Suppl 1:303-10.

30. The Actions of Lyophilized Apple Peel on the Electrical Activity and Organization of the Ventricular Syncytium of the Hearts of Diabetic Rats. J Diabetes Res. 2016;2016:8178936.

 

 

BREAKING NEWS: EDITORS’ PICKS

  • The Major Link Between Obesity and Diabetes. From Dr. Louis Venter. May 6, 2016 
  • Leptin plays a direct role in cardiovascular disease in obesity. Circulation, October 7, 2015
    While high levels of the satiety hormone leptin don’t help obese individuals lose weight, they do appear to directly contribute to their cardiovascular disease.
  • Adiponectin supplementation in pregnant mice prevents the adverse effects of maternal obesity on placental function and fetal growth. PNAS, 2015 Sept
    As obesity rates for pregnant women continue to climb, scientists have discovered that increasing a specific hormone during pregnancy can reduce or eliminate the chances that the baby will become obese as well.
  • High dietary fiber intake linked to health promoting short chain fatty acids. Gut, September 29, 2015
    Eating a lot of fibre-rich foods, such as fruit, vegetables, and legumes–typical of a Mediterranean diet–is linked to a rise in health promoting short chain fatty acids (SCFAs), which include acetate, propionate, and butyrate, are produced by bacteria in the gut during fermentation of insoluble fibre from dietary plant matter. SCFAs have been linked to health promoting effects, including a reduced risk of inflammatory diseases, diabetes, and cardiovascular disease.
  • Progress of Diabetic Severity and Risk of Dementia. Journal of Clinical Endocrinology & Metabolism, July 9, 2015
    People who have diabetes and experience high rates of complications are more likely to develop dementia as they age than people who have fewer diabetic complications.
  • Measuring kidney health could better predict heart disease risk. Lancet Diabetes and Endocrinology. May 29, 2015
    Simple measures of kidney function and damage may be just as good at predicting who is at risk for heart failure and death from heart attack and stroke as traditional tests of cholesterol levels and blood pressure, new research suggests.
  • Genetically elevated triglyceride level associated with protection against type 2 diabetes. PLOS Genetics, May 28, 2015
    It demonstrates that triglyceride-increasing alleles are associated with decreased type-2 diabetes incidence. The studied genes therefore appear to both increase triglyceride levels and decrease type-2 diabetes risk. Although no single gene appeared to be driving this trend, several, including a variant near the APOA1 gene, stood out as potentially interesting to this finding.
  • Diabetes debate: Triglycerides form in liver despite insulin resistance. PNAS, January 5, 2015
    Triglycerides are produced in the liver independent of insulin action in the liver, solving one of the great mysteries of type 2 diabetes.
  • Leptin also influences brain glial cells to control appetite. Nature Neuroscience, June 1, 2014
    Twenty years after the hormone leptin was found to regulate metabolism, appetite, and weight through brain cells called neurons, researchers have found that the hormone also acts on other types of cells, glial cells, which provide the main barrier between the periphery and the brain, and therefore could be targeted for drugs that treat metabolic disorders, including obesity and diabetes.
  • Obesity rates climbing worldwide. The Lancet, May 28, 2014
    Worldwide, there has been a startling increase in rates of obesity and overweight in both adults (28% increase) and children (up by 47%) in the past 33 years, with the number of overweight and obese people rising from 857 million in 1980 to 2.1 billion in 2013, according to a most comprehensive global study to date.

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