Infection and Immunity

2016 Dec

1. Capsule Design for Blue Light Therapy against Helicobacter pylori. PLoS One. 2016 Jan 27;11(1):e0147531.

3. An Integrated Metabolomic and Microbiome Analysis Identified Specific Gut Microbiota Associated with Fecal Cholesterol and Coprostanol in Clostridium difficile Infection. PLoS One. 2016 Feb 12;11(2):e0148824.

5. Ombitasvir, paritaprevir, ritonavir, dasabuvir and ribavirin in cirrhosis after complete destruction of hepatocellular carcinoma. World J Gastroenterol. 2016 Feb 28;22(8):2630-5.

7. Validation of research trajectory 1 of an Exposome framework: Exposure to benzo(a)pyrene confers enhanced susceptibility to bacterial infection. Environ Res. 2016 Apr;146:173-84.

9. Clinical Outcomes of Patients with HIV Undergoing Lead Extraction for Infectious and Noninfectious Indications. Pacing Clin Electrophysiol. 2016 Feb;39(2):122-7.

11. Persistence of non-typeable Haemophilus influenzae in the pharynx of children with adenotonsillar hypertrophy after treatment with azithromycin. Pathogens and Disease. 2016 Feb;74(1):ftv106.

14. Development of an in vitro model of the early-stage bovine tuberculous granuloma using Mycobacterium bovis-BCG. Vet Immunol Immunopathol. 2015 Dec 15;168(3-4):249-57.

15. Full Length Single Chain Fc Protein (FLSC IgG1) as a Potent Antiviral Therapy Candidate: Implications for In Vivo Studies. AIDS Res Hum Retroviruses. 2016 Feb;32(2):178-86.

17. Improvements and Limitations of Humanized Mouse Models for HIV Research: NIH/NIAID “Meet the Experts” 2015 Workshop Summary. AIDS Res Hum Retroviruses. 2016 Feb;32(2):109-19.

19. “My Favourite Day Is Sunday”: Community Perceptions of (Drug-Resistant) Tuberculosis and Ambulatory Tuberculosis Care in Kara Suu District, Osh Province, Kyrgyzstan. PLoS One. 2016 Mar 28;11(3):e0152283.

21. Emergence of reticuloendotheliosis virus in pigeons in Guangdong province, southern China. Arch Virol. 2016 Jul;161(7):2007-2011.

23. Nonactivated Protein C in the Treatment of Neonatal Sepsis: A Retrospective Analysis of Outcome. Pediatr Infect Dis J. 2016 Sep;35(9):967-71.

25. The Phospholipid:Diacylglycerol Acyltransferase Lro1 Is Responsible for Hepatitis C Virus Core-Induced Lipid Droplet Formation in a Yeast Model System. PLoS One. 2016 Jul 26;11(7):e0159324.

27. Antigen Receptor-Intrinsic Non-Self: The Key to Understanding Regulatory Lymphocyte-Mediated Idiotypic Control of Adaptive Immune Responses. Crit Rev Immunol. 2016;36(1):13-56.



2. Development of a Murine Infection Model with Leishmania killicki, Responsible for Cutaneous Leishmaniosis in Algeria: Application in Pharmacology. Biomed Res Int. 2016;2016:7985104.

4. Detection of natural infection of Leishmania donovani (Kinetoplastida: Trypanosomatidae) in Phlebotomus argentipes (Diptera: Psychodidae) from a forest ecosystem in the Western Ghats, India, endemic for cutaneous leishmaniasis. Acta Trop. 2016 Apr;156:95-9.

6. Social class based on occupation is associated with hospitalization for A(H1N1)pdm09 infection. Comparison between hospitalized and ambulatory cases. Epidemiol Infect. 2016 Mar;144(4):732-40.

8. Efficacy and persistent activity of moxidectin against natural Muellerius capillaris infection in goats and pathological consequences of muelleriosis. Vet Parasitol. 2016 Mar 15;218:98-101.

10. Neutrophil-to-lymphocyte ratio in the differential diagnosis of acute bacterial meningitis. Eur J Clin Microbiol Infect Dis 2016 Mar; 35(3):397-403.

12. A Putative Non-Canonical Ras-Like GTPase from P. falciparum: Chemical Properties and Characterization of the Protein. PLoS One. 2015 Nov 5;10(11):e0140994.

16. Characterization of a serine hydrolase targeted by acyl-protein thioesterase inhibitors in Toxoplasma gondii. J Biol Chem. 2013 Sep 20;288(38):27002-18.

18. Spondylodiscitis severity code: scoring system for the classification and treatment of non-specific spondylodiscitis. Eur Spine J. 2016 Apr;25(4):1012-20.

20. TLR4 induces CCR7-dependent monocytes transmigration through the blood-brain barrier. J Neuroimmunol. 2016 Jun 15;295-296:12-7.

22. PGC-1α-Dependent Mitochondrial Adaptation Is Necessary to Sustain IL-2-Induced Activities in Human NK Cells. Mediators Inflamm. 2016;2016:9605253.

24. Modeling and predicting drug resistance rate and strength. Eur J Clin Microbiol Infect Dis.2016 Aug;35(8):1259-1267.

26. Analysis of the beta-propiolactone sensitivity and optimization of inactivation methods for human influenza H3N2 virus. J Virol Methods.2016 Sep;235:105-111




New analysis of the influenza A virus shows potential for developing new anti-viral drugs which are more likely to be universally effective against the flu virus originating from avian, swine or human virus strains.

Around 1 in 5 of the population were infected in both recent outbreaks of seasonal flu and the 2009 H1N1 influenza pandemic, but just 23% of these infections caused symptoms, and only 17% of people were ill enough to consult their doctor.

One person having a rare combination of both lupus and HIV, has the unique ability to fight HIV. This provided key insights into an immune response that researchers now hope to trigger with a vaccine, according to new findings.

The immune cells of 12 HIV positive patients have been successfully genetically engineered by researchers to resist infection, and decrease the viral loads of some patients taken off antiretroviral drug therapy (ADT) entirely -— including one patient whose levels became undetectable. This it the first published report of any gene editing approach in humans.

A KwaZulu-Natal woman’s body responded to her HIV infection by making potent antibodies (called broadly neutralizing antibodies, because they are able to kill multiple strains of HIV from across the world). Researchers identified these antibodies in her blood and then duplicated them by cloning the antibodies in the laboratory. The cloned antibodies were then used in a series of experiments in the laboratory to elucidate the pathway followed by her immune system to make these potent antibodies.

The antibiotics, called spectinamides, were created by changing the chemical structure of an existing antibiotic, spectinomycin, which does not work against TB.


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