Product Description
AAK1 Polyclonal Antibody |ELK Biotechnology Antibodies | is available at Gentaur for Next Week Delivery
Product Background: AP2 associated kinase 1(AAK1) Homo sapiens Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008],
Source: Rabbit
Application: WB,IHC-p,IF,ELISA
Species Reactivity: Human,Mouse,Rat,Monkey
Recommended Dilution: N/A
Immunogenecity: The antiserum was produced against synthesized peptide derived from human AAK1. AA range:271-320
Speceficity: N/A
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype: N/A
Observed Brand: 94 kDa
Cellular Localization: N/A
Alternative Names: AAK1; KIAA1048; AP2-associated protein kinase 1; Adaptor-associated kinase 1