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Product Description
ARI1A Polyclonal Antibody |ELK Biotechnology Antibodies | is available at Gentaur for Next Week Delivery
Product Background: AT-rich interaction domain 1A(ARID1A) Homo sapiens This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through eit
Source: Rabbit
Application: IHC-p
Species Reactivity: Human,Mouse
Recommended Dilution: N/A
Immunogenecity: Synthesized peptide derived from human protein . at AA range: 1270-1350
Speceficity: N/A
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype: N/A
Observed Brand: 251 kDa
Cellular Localization: N/A
Alternative Names: N/A
