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Product Description
BAM32 (phospho Tyr139) Polyclonal Antibody |ELK Biotechnology Antibodies | is available at Gentaur for Next Week Delivery
Product Background: function:May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K.,induction:Upon B-cell activation.,PTM:Phosphorylated on tyrosine residues.,similarity:Contains 1 PH domain.,similarity:Contains 1 SH2 domain.,subcellular location:Membrane-associated after cell stimulation leading to its translocation.,subunit:Interacts with PtdIns(3,4,5)P3 and PLCG2. In vitro, interacts with PtdIns(3,4)P2.,tissue specificity:Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.,
Source: Rabbit
Application: WB,IHC-p,IF,ELISA
Species Reactivity: Human,Mouse
Recommended Dilution: N/A
Immunogenecity: The antiserum was produced against synthesized peptide derived from human DAPP1 around the phosphorylation site of Tyr139. AA range:105-154
Speceficity: N/A
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype: N/A
Observed Brand: 32 kDa
Cellular Localization: N/A
Alternative Names: DAPP1; BAM32; HSPC066; Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide; hDAPP1; B lymphocyte adapter protein Bam32; B-cell adapter molecule of 32 kDa
