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Product Description
COL1A2 Polyclonal Antibody |ELK Biotechnology Antibodies | is available at Gentaur for Next Week Delivery
Product Background: collagen type I alpha 2 chain(COL1A2) Homo sapiens This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008],
Source: Rabbit
Application: WB,IHC-p,IF,ELISA
Species Reactivity: Human
Recommended Dilution: N/A
Immunogenecity: The antiserum was produced against synthesized peptide derived from human Collagen I alpha2. AA range:471-520
Speceficity: N/A
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype: N/A
Observed Brand: 125 kDa
Cellular Localization: N/A
Alternative Names: COL1A2; Collagen alpha-2(I) chain; Alpha-2 type I collagen
