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Product Description
COX2/Cyclooxygenase 2 Rabbit pAb |ELK Biotechnology Antibodies | is available at Gentaur for Next Week Delivery
Product Background: Prostaglandin-endoperoxide synthase 2, also known as cyclooxygenase-2 or simply COX-2, is an enzyme that in humans is encoded by the PTGS2 gene. There are two isozymes of COX encoded by distinct gene products: a constitutive COX-1 (this enzyme) and an inducible COX-2, which differ in their regulation of expression and tissue distribution. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors. A splice variant of COX-1 termed COX-3 was identified in the CNS of dogs, but does not result in a functional protein in humans. Two smaller COX-1-derived proteins (the partial COX-1 proteins PCOX-1A and PCOX-1B) have also been discovered, but their precise roles are yet to be described.
Source: Rabbit
Application: WB, IHC
Species Reactivity: Human
Recommended Dilution: WB 1:1,000 IHC 1:100
Immunogenecity: Synthetic Peptide
Speceficity: Human
Purification: N/A
Isotype: IgG
Observed Brand: 70 kDa
Cellular Localization: N/A
Alternative Names: Cyclooxygenase 2, GRIPGHS, hCox 2, PGG/HS, PGH synthase 2, PGHS 2, PHS 2, PHS II, Prostaglandin G/H synthase 2, Prostaglandin H2 synthase 2, PTGS2
Gene ID (Human): 5743
Human Swiss-Protein No. : P35354
