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Product Description
E2F-1 (Acetyl-Lys120) Polyclonal Antibody |ELK Biotechnology Antibodies | is available at Gentaur for Next Week Delivery
Product Background: E2F transcription factor 1(E2F1) Homo sapiens The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can media
Source: Rabbit
Application: WB,ELISA
Species Reactivity: Human:K120,Mouse:K115,Rat:K118
Recommended Dilution: N/A
Immunogenecity: Synthesized acetyl-peptide from human protein at AA range: 100-170
Speceficity: N/A
Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Isotype: N/A
Observed Brand: 70 kDa
Cellular Localization: N/A
Alternative Names: E2F1 RBBP3
