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Product Description
E2F-4/5 Polyclonal Antibody |ELK Biotechnology Antibodies | is available at Gentaur for Next Week Delivery
Product Background: E2F transcription factor 4(E2F4) Homo sapiens The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein binds to all three of the tumor suppressor proteins pRB, p107 and p130, but with higher affinity to the last two. It plays an important role in the suppression of proliferation-associated ge
Source: Rabbit
Application: WB,IHC-p,ELISA
Species Reactivity: Human,Mouse,Rat,Monkey
Recommended Dilution: N/A
Immunogenecity: The antiserum was produced against synthesized peptide derived from human E2F4. AA range:51-100
Speceficity: N/A
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype: N/A
Observed Brand: 44 kDa
Cellular Localization: N/A
Alternative Names: E2F4; Transcription factor E2F4; E2F-4; E2F5; Transcription factor E2F5; E2F-5
