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Product Description
Integrin β4 Polyclonal Antibody |ELK Biotechnology Antibodies | is available at Gentaur for Next Week Delivery
Product Background: integrin subunit beta 4(ITGB4) Homo sapiens Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Source: Rabbit
Application: WB,ELISA
Species Reactivity: Human,Mouse,Rat
Recommended Dilution: N/A
Immunogenecity: The antiserum was produced against synthesized peptide derived from the Internal region of human ITGB4. AA range:641-690
Speceficity: N/A
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype: N/A
Observed Brand: 200 kDa
Cellular Localization: N/A
Alternative Names: ITGB4; Integrin beta-4; GP150; CD104
