Product Description
Kininogen 1 Rabbit pAb |ELK Biotechnology Antibodies | is available at Gentaur for Next Week Delivery
Product Background: Kininogens are inhibitors of thiol proteases; HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes; the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects. LMW-kininogen inhibits the aggregation of thrombocytes; LMW-kininogen is in contrast to HMW-kininogen not involved in blood clottingUCHL1, UCHL3, UCHL5/UCH37, and BRCA-1-associated protein-1 (BAP1) belong to the UCH family of DUBs, which all posses a conserved catalytic domain (UCH domain) of about 230 amino acids. UCHL1 is abundantly expressed in neuronal tissues and testes.
Source: Rabbit
Application: WB, IHC
Species Reactivity: Human,Mouse,Rat
Recommended Dilution: WB 1:1500-1,000 IHC 1:100-200
Immunogenecity: Recombinant Protein
Speceficity: Human
Purification: N/A
Isotype: IgG
Observed Brand: 45-120 kDa
Cellular Localization: Secreted
Alternative Names: BDK, Fitzgerald factor, HMWK, Ile Ser Bradykinin Bradykinin, Kallidin I Lysyl bradykinin, kininogen 1, KNG, KNG1
Gene ID (Human): 3827
Human Swiss-Protein No. : P01042