Autoimmune disease

2016

1. Home-based training to improve manual dexterity in patients with multiple sclerosis: A randomized controlled trial. Mult Scler. 2015 Oct;21(12):1546-56

3. Glycomacropeptide is a prebiotic that reduces Desulfovibrio bacteria, increases cecal short-chain fatty acids, and is anti-inflammatory in mice. Am J Physiol Gastrointest Liver Physiol. 2015 Oct 1;309(7):G590-601.

5. A Case of Stiff Person Syndrome: Immunomodulatory Effect of Benzodiazepines: Successful Rituximab and Tizanidine Therapy. Medicine. 2015 Jun;94(23):e954.

7. Experimental autoimmune encephalomyelitis and age-related correlations of NADPH oxidase, MMP-9, and cell adhesion molecules: The increased disease severity and blood-brain barrier permeability in middle-aged mice. J Neuroimmunol. 2015 Oct 15;287:43-53.

9. Chronic exposure to water pollutant trichloroethylene increased epigenetic drift in CD4+ T cells. Epigenomics. 2016,8(5)633-649.

2. Recovery from experimental autoimmune uveitis promotes induction of antiuveitic inducible Tregs. J Leukoc Biol. 2015 Jun;97(6):1101-9.

4. Metagenomic Analysis of Crohn’s Disease Patients Identifies Changes in the Virome and Microbiome Related to Disease Status and Therapy, and Detects Potential Interactions and Biomarkers. Inflamm Bowel Dis. 2015 Nov;21(11):2515-32.

6. Aptamer BC007 for neutralization of pathogenic autoantibodies directed against G-protein coupled receptors: A vision of future treatment of patients with cardiomyopathies and positivity for those autoantibodies. Atherosclerosis. 2016 Jan;244:44-7.

8. Novel receptor-derived cyclopeptides to treat heart failure caused by anti-β1-adrenoceptor antibodies in a human-analogous rat model. PLoS One. 2015 Feb 20;10(2):e0117589.

10. Effect of a family history of Psoriasis and age on comorbidities and quality of life in patients with moderate to severe Psoriasis: Results from the ARIZONA study. J Dermatol.2016 Apr;43(4):395-401.

2015 Oct

1. Genetic sharing and heritability of paediatric age of onset autoimmune diseases. Nat Commun. 2015 Oct 9;6:8442.

3. Impact of metabolic syndrome on the hospitalization rate of Crohn’s disease patients seen at a tertiary care center: a retrospective cohort study. Digestion. 2015;91(3):257-62.

5. Evidence that a neutrophil-keratinocyte crosstalk is an early target of IL-17A inhibition in psoriasis. Exp Dermatol. 2015 Jul;24(7):529-35.

7. MiR-126: a novel route for natalizumab action? Mult Scler. 2014 Sep;20(10):1363-70.

9. Thyroid autoimmunity as a window to autoimmunity: An explanation for sex differences in the prevalence of thyroid autoimmunity. Journal of Theoretical Biology. 2015 Jun 21;375:95-100.

2. The inhibitory effect of secretory leukocyte protease inhibitor (SLPI) on formation of neutrophil extracellular traps. J Leukoc Biol. 2015 Jul;98(1):99-106.

4. Ten-year follow-up of a DOCK8-deficient child with features of systemic lupus erythematosus. Pediatrics. 2014 Nov;134(5):e1458-63.

6. Obstructive sleep apnea and fatigue in patients with multiple sclerosis. J Clin Sleep Med. 2014 Feb 15;10(2):155-62.

8. Diffusion-weighted magnetic resonance for assessing ileal Crohn’s disease activity. Inflamm Bowel Dis. 2014 Sep;20(9):1575-83.

10. Multicontrast MRI Quantification of Focal Inflammation and Degeneration in Multiple Sclerosis. Biomed Res Int. 2015;2015:569123.

ARCHIVE

BREAKING NEWS: Editors’ Picks

The DNA Sensor AIM2 Maintains Intestinal Homeostasis via Regulation of Epithelial Antimicrobial Host Defense. Cell Reports, November 19, 2015
A pathogen-sensing molecule (AIM2) plays a vital role in keeping gastrointestinal (GI) systems healthy, valuable in treating conditions such as inflammatory bowel diseases (IBDs) and colorectal cancer.
New strategies to decrease immune responses in inflammatory bowel disease. Nature Communications, November 10, 2015
Novel insights into the expression of the ecto-enzyme CD39 on immune cells and further illuminate the role of purinergic signaling in IBD.
Genetic sharing and heritability of paediatric age of onset autoimmune diseases. Nature Communications, October 9, 2015
Scientists have calculated more precise measurements of heritability — the influence of underlying genes — in nine autoimmune diseases that begin in childhood, better predicting a child’s risk for associated autoimmune diseases.
MicroRNA214 is Associated with Progression of Ulcerative Colitis, and Inhibition Reduces Development of Colitis and Colitis-associated Cancer in Mice. Gastroenterology, July 23, 2015
High levels of microRNA-214 are typically seen in UC patients, who have an increased risk of developing colon cancer. A groundbreaking experimental therapy has been discovered that has the ability to suppress the development of ulcerative colitis.
Novel mechanism for Crohn’s disease uncovered. Gut, April 23, 2015
the presence of certain intestinal bacteria also plays a role: bacterial imbalance in the gut can lead to an inflammation similar to Crohn’s disease, and this can be transmitted to other animals.

Autoimmune disease