Product Description
14-3-3 ε Polyclonal Antibody |ELK Biotechnology Antibodies | is available at Gentaur for Next Week Delivery
Product Background: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon(YWHAE) Homo sapiens This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008],
Source: Rabbit
Application: WB,IHC-p
Species Reactivity: Mouse,Rat
Recommended Dilution: N/A
Immunogenecity: Recombinant Protein of 14-3-3 ε
Speceficity: N/A
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype: N/A
Observed Brand: 28 kDa
Cellular Localization: N/A
Alternative Names: YWHAE; 14-3-3 protein epsilon; 14-3-3E