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Product Description
Arkadia Polyclonal Antibody |ELK Biotechnology Antibodies | is available at Gentaur for Next Week Delivery
Product Background: ring finger protein 111(RNF111) Homo sapiens The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012],
Source: Rabbit
Application: WB,ELISA
Species Reactivity: Human,Mouse
Recommended Dilution: N/A
Immunogenecity: The antiserum was produced against synthesized peptide derived from human RNF111. AA range:901-950
Speceficity: N/A
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype: N/A
Observed Brand: 110 kDa
Cellular Localization: N/A
Alternative Names: RNF111; E3 ubiquitin-protein ligase Arkadia; RING finger protein 111
