Product Description
CD10 Rabbit pAb |ELK Biotechnology Antibodies | is available at Gentaur for Next Week Delivery
Product Background: CD10 is a zinc-dependent metalloprotease enzyme that degrades a number of small secreted peptides, most notably the amyloid beta peptide whose abnormal misfolding and aggregation in neural tissue has been implicated as a cause of Alzheimer's disease. Synthesized as a membrane-bound protein, the neprilysin ectodomain is released into the extracellular domain after it has been transported from the Golgi apparatus to the cell surface. In neurons, neprilysin is regulated by the protein nicastrin, a component of the gamma secretase complex that performs a necessary step in processing amyloid precursor protein to amyloid beta.
Source: Rabbit
Application: IHC
Species Reactivity: Human,Rat,Mouse
Recommended Dilution: IHC 1:200-500
Immunogenecity: Recombinant Protein
Speceficity: Human
Purification: N/A
Isotype: IgG
Observed Brand: 85 kDa
Cellular Localization: Cell membrane
Alternative Names: CALLA, Enkephalinase,MME,NEP, Neutral endopeptidase antibody
Gene ID (Human): 4311
Human Swiss-Protein No. : P08473