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Product Description
HUWE1 Polyclonal Antibody |ELK Biotechnology Antibodies | is available at Gentaur for Next Week Delivery
Product Background: HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase(HUWE1) Homo sapiens This gene encodes a protein containing a C-terminal HECT (E6AP type E3 ubiquitin protein ligase) domain that functions as an E3 ubiquitin ligase. The encoded protein is required for the ubiquitination and subsequent degradation of the anti-apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2-related)). This protein also ubiquitinates the p53 tumor suppressor, core histones, and DNA polymerase beta. Mutations in this gene are associated with Turner type X-linked syndromic mental retardation. [provided by RefSeq, Aug 2013],
Source: Rabbit
Application: IHC-p
Species Reactivity: Human,Mouse
Recommended Dilution: N/A
Immunogenecity: Synthesized peptide derived from part region of human protein
Speceficity: N/A
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype: N/A
Observed Brand: 481 kDa
Cellular Localization: N/A
Alternative Names: N/A
