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Product Description
IGF-IR (phospho Tyr1346) Polyclonal Antibody |ELK Biotechnology Antibodies | is available at Gentaur for Next Week Delivery
Product Background: insulin like growth factor 1 receptor(IGF1R) Homo sapiens This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014],
Source: Rabbit
Application: IHC-p,ELISA
Species Reactivity: Human,Mouse,Rat
Recommended Dilution: N/A
Immunogenecity: The antiserum was produced against synthesized peptide derived from human IGF1R around the phosphorylation site of Tyr1346. AA range:1311-1360
Speceficity: N/A
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype: N/A
Observed Brand: N/A kDa
Cellular Localization: N/A
Alternative Names: IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221
